Guardian: GM salmon & other altered food contain high levels of cancer-causing agents *

Guardian
07.09.2010
By Dan Kennedy

Who dares question the industrial food system over GM salmon?

Genetically modified salmon is deemed safe for human consumption – despite higher levels of a suspected carcinogen

“If salmon and milk and a whole range of edible food-like substances yet to come contain elevated levels of IGF-1, when, exactly, are we supposed to start worrying?”

Last Friday, though, the US Food and Drug Administration (FDA) took a potentially dangerous step. The agency ruled that salmon whose genes have been altered so that they grow more rapidly than their wild counterparts are safe for human consumption.

it may have foisted upon the public yet another cancer risk.

According to a report in the New York Times, FDA scientists found that the altered fish, developed by AquaBounty Technologies, based in the Boston area, were unlikely to escape into the environment and cross-breed with native schools of Atlantic salmon. The agency also found that even though the genetically altered salmon carry elevated levels of insulin-like growth factor-1 (IGF-1), a suspected carcinogen, those levels are so minute that they pose no health risk.

Precautions aside, it requires considerably more than the customary level of naivety to believe wild salmon wouldn’t be contaminated by their laboratory-designed cousins.

But it is the IGF-1 about which we truly ought to be concerned, because the FDA’s finding is evidence of an unacceptably narrow focus. The substance occurs naturally in salmon and other animal products, and the agency tells us that the genetically altered fish contains only a tiny amount more. Yet, by considering such matters one at a time, the FDA may well be introducing us to many tiny risks that start adding up to a very real risk.

This isn’t the first time we’ve had to worry about IGF-1. In the 1990s, the FDA approved the use of genetically engineered recombinant bovine-growth hormone (rBGH, also known as rBST) to induce cows to produce more milk. It was, and is, a controversial practice

My reporting convinced me that rBGH posed a greater risk to cows than to humans, as the unnaturally high rate of milk production stressed the animals, sometimes resulting in an infection known as mastitis. (Which is treated with antibiotics. Which enter the food supply. Which – well, you get the picture.)

But cows given rBGH, like genetically altered salmon, also have higher levels of IGF-1, some of which makes its way into the milk. But if salmon and milk and a whole range of edible food-like substances (to use Michael Pollan’s phrase) yet to come contain elevated levels of IGF-1, when, exactly, are we supposed to start worrying?

In addition to being linked to colon, prostate and breast cancer, IGF-1 is a trigger for puberty, which has led to speculation that too much could cause puberty to come about prematurely. IGF-1 also has its uses, both legitimate and dubious. When human-growth hormone is administered as a corrective to children with certain rare types of hormonally based dwarfism, it stimulates the production of IGF-1, which in turn boosts growth.

As it happens, I recently finished Jared Diamond’s celebrated book Guns, Germs and Steel, which, among other things, explains the civilising effects of domesticating – that is, genetically altering – certain plants and animals. But genetic engineering as practiced in the Fertile Crescent thousands of years ago contained within it certain limits that ensured some degree of safety. Even the green revolution of the 1960s was based on tried-and-true methods of selective breeding.

By contrast, modern scientific tools allow genetic engineers to try just about anything in order to see what will happen. AquaBounty’s Atlantic salmon, for instance, contain a growth-hormone gene from Chinook salmon – and another gene from an entirely different fish, the ocean pout, which has the effect of keeping that growth-hormone gene switched on. The result is an alien creature, unknown in the natural world.

a host of consumer organisations is fighting against genetically modified salmon.

Trouble is, there are few politicians willing to incur the wrath (and eschew the campaign contributions) of the American industrial food system.

In the end, the battle over genetically modified salmon is emblematic of a larger problem: an ongoing shift away from real food in favour of substances concocted in a lab.

Full article

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